Adipose Stem Cell… ‘Regenerative Medicine’ in 21st Century

    Adipose tissue is one of the richest sources of stem cells in the body, so it is no coincidence that it is an attractive choice for many therapeutic purposes, including the regeneration and repair of acute and chronically damaged tissues. Another alluring factor is because adipose stem cells are harvested from the patient’s own body, there are no ethical or moral issues involved in the procedure.


    Stem cell therapy is ‘modern medicines’ major player when it comes to regenerative medicine and tissue engineering. Many medical practitioners also prefer adipose-derived stem cells (ASCs) over other types of stem cells because of the large number available to harvest. The number of ASCs within adipose tissue reaches more than hundreds of times compared with BMSCs (bone marrow stromal/stem stem cells) contained in the same amount of bone marrow.

    It is also important to know the characteristics of ASCs for successful clinical application. There are several unique features of ASCs which are known common characteristic of mesenchymal stem cells (MSCs). Mesenchymal stem cells are multipotent stromal cells that can differentiate into a variety of cell types, including: osteoblasts (bone cells), chondrocytes (cartilage cells), and adipocytes (fat cells). Cellular plasticity is one of the most important features of ASCs, the cells also have a special function of immune modulation and immunosuppression. Strong angiogenic potential is another important nature of ASCs. In many reports, ASCs are known not only to be differentiated into osteoblasts, chondrocytes, vascular endothelial cells, but also to be cardiomyocytes and neuronal cells. In conclusion, the new knowledge of ASCs is going to impact on the regenerative medicine

    What is an Autologous Adipose Stem Cell Procedure?

    Autologous means that the donor and the recipient are the same person. A small sample of Adipose tissue (fat) is removed from above the love handles (superior Iliac spine) or abdomen under a local anesthetic. The stem cells are then extracted from the removed adipose tissue.

    Benefits of ADSC: Stem cells play an integral part in wound healing and regeneration of tissue at the cellular level.

    How do the stem cells work?

    Stem Cells are infused into the bloodstream and injected into localized tissues.
    The stem cells are attracted to signals from areas of inflammation.
    Distressed signals trigger stem cells to differentiate.
    Differentiating cells begin to integrate with target tissues or organs, promoting accelerated healing.


    The Major Advantages of Adipose Stem Cell Therapy:

    – Today’s technology allows us to complete the entire procedure on the same day.
    –  High Yield: A high-dose of stem cells can be obtained in just a couple of hours.
    –  Mesenchymal stem cell yields from peripheral fat are much higher than from bone marrow.
    –  Patients receive their own autologous cells, so there is a very low risk of immune rejection.
    –  A minimally invasive outpatient procedure makes it easier to harvest from fat than from bone marrow and is more comfortable for patients.
    –  Harvested from waste material from a liposuction procedure provides a good opportunity to get rid of unwanted fat.

    Why Choose an Adipose Stem Cell Procedure?

    Adipose-derived mesenchymal stem cells are easier to harvest than bone marrow and can be obtained in much larger quantities. In addition, it is much less painful and involves lower risks.

    There is a much shorter time from extraction to the administration of treatment. No culturing or manipulation is needed using our procedure, as opposed to a bone marrow extraction which requires days or weeks to reach the necessary therapeutic threshold.

    Are There Detrimental Side Effects from an Adipose Stem Cell Procedure?

    No, the adipose tissue is extracted from the patient’s own body so no ‘foreign’ donors are used. This minimizes the potential for immune rejection. Our procedure is performed completely in-house and administered by our doctors.

    Is an Autologous Adipose Stem Cell Procedure Safe?

    Yes… because the adipose tissue is removed from one’s own body via sterile technique and remains in a controlled environment there are no problems with cell rejection or disease transmission. Once the cells have been harvested they are purified and assessed for quality before being reintroduced back in the patient. Since the stem cells come from the patient there is no possibility for rejection.

    Is the procedure we use at APEX a significant improvement on other treatments currently available?

    Yes! We can now obtain the stem cells from a fat sample. This in-clinic treatment is completed the same day, and there is no need to ship samples to an outside laboratory and wait days for the cells to be returned for an injection on a second visit. This faster process provides increased stem cell counts, without manipulation.

    What You Can Expect When Visiting the APEX Stem Cell Rejuvenation Center:

    Consultation: Each patient will receive an in-depth consultation prior to their treatment: History, Medications, Patient desires and expected outcomes will be discussed with our highly-qualified doctor.

    Harvest: Using a tumescent anesthetic, a sample of adipose tissue is collected from the patient.
    Stem Cells: Our laboratory staff will isolate the Adult Stem Cells (ASCs) and other ‘progenitor cells in a sterile environment from the collected fat sample ensuring that no contamination occurs. There is a difference between aseptic and sterile techniques, Sterile is the absence of ALL microbes, Aseptic is just the absence of disease producing microbes. So, it is important to note that sterility means that the cells are not exposed to air particles and contaminants.
    Preparation: If the doctor wishes, she/he will offer antioxidant and nutritional IV’s prior to infusion to prepare the patient for the therapy.
    Infuse: The cells are then administered back to the patient through one or more of the following modes of administration:
    Intravenous: The Stem Cells are administered via an intravenous push.
    Localized: The Stem Cells are administered directly into a localized area.


    Adipose stem cells can be used for:
    – Personalized medical treatments; menstrual problems, sleeping problems, stress, neck and shoulder pain, back and lower-back pain, immune system malfunction, constipation, anemia, hormone imbalance, sexual dysfunction, arthritis and connective tissue degeneration, chronic migraine, headache, coronary arteries, blood circulatory system, degeneration of the brain, heart, kidneys, liver and digestive system.
    – Beauty- healthy skin, to make skin smoother, softer, brighter and more youthful.
    – Autologous fat transfer to the face, breasts, or buttocks.


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